Stem cells may be used for healing damaged lungs
Healing Damaged Lungs with Stem Cells
A new study from the Weizmann Institute of Science reveals promising results using stem cells to repair damaged lung tissue. This breakthrough offers hope for treating conditions like bronchitis, asthma, cystic fibrosis, and emphysema, which collectively affect millions globally.
Bone Marrow Stem Cells for Lung Tissue Regeneration
The study focuses on similarities between lung and bone marrow stem cells. Researchers at the Weizmann Institute, led by Professor Yair Reisner, successfully transplanted bone marrow stem cells into mice with lung damage. These stem cells migrated to damaged areas, differentiated into lung tissue, and continued to generate new cells up to 16 weeks post-transplantation.
Future Directions: Lung-Specific Induced Pluripotent Stem Cells (iPSCs)
Advantages of iPSCs Over Bone Marrow Stem Cells
In related research, scientists at Boston University Medical Center generated lung-disease specific induced pluripotent stem cells (iPSCs) from patients with conditions like emphysema and cystic fibrosis. iPSCs offer advantages such as easier cultivation and genetic compatibility, minimizing the risk of rejection in transplants.
Potential for Transplantation and Lung Tissue Differentiation
Studies show that iPSCs can differentiate into endoderm cells, precursors to lung tissue, offering a promising avenue for future treatments of lung diseases.
Conclusion
The research underscores the potential of stem cells, both from bone marrow and induced pluripotent sources, to revolutionize the treatment of lung diseases. Ongoing studies aim to refine these techniques and explore the creation of a bank of lung-specific stem cells for clinical use.
References
- Chava Rosen, Elias Shezen, Anna Aronovich, Yael Zlotnikov Klionsky et al. – Preconditioning allows engraftment of mouse and human embryonic lung cells, enabling lung repair in mice, Nature Medicine, 2015, Link.
- Aba Somers, Jyh-Chang Jean, Cesar A. Sommer, Amel Omari et al. – Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette, Stem Cells, 2010, 28 (10):1728, Link.
This structure ensures each section is clearly delineated for SEO purposes, incorporating keywords like “stem cells,” “lung tissue regeneration,” “induced pluripotent stem cells,” and specific study references.
- Published in Corporate News / Blog
Adult tissues that serve as sources for stem cells
Where Do Adult Stem Cells Come From?
Adult stem cells are garnering significant interest in the scientific community due to their ability to self-renew and differentiate into various types of cells and tissues. Unlike embryonic stem cells, which can differentiate into multiple cell types, adult stem cells typically generate tissues specific to their origin. This focus on adult stem cells has intensified amidst ethical concerns surrounding embryonic stem cell research, making them pivotal in the study of degenerative conditions such as osteoarthritis, muscular dystrophy, and Alzheimer’s disease.
Sources of Adult Stem Cells
Adult stem cells are found in several tissues, each offering potential therapeutic applications:
Neural Stem Cells (NSCs)
Neural stem cells are multipotent cells that can generate the central nervous system. Recent studies, including research by Japanese scientists, demonstrate their potential to replace dying neurons in conditions like multiple sclerosis and Parkinson’s disease [1].
Hematopoietic Stem Cells (HSCs)
Hematopoietic stem cells, derived from blood or bone marrow, can differentiate into various specialized cells such as white blood cells and red blood cells. They play a crucial role in immune response and blood clotting.
Skeletal Stem Cells (STCs)
Found in bone marrow, skeletal stem cells give rise to bone cells (osteoblasts), cartilage, and hematopoietic stroma, supporting bone structure and function.
Intestinal Stem Cells (ISCs)
ISCs, located in the lining of the intestines, continuously divide throughout life. They are implicated in intestinal cancer development but also offer regenerative potential for treating gastrointestinal disorders.
Liver Stem Cells
In the liver, hepatocytes exhibit stem cell-like behavior during regeneration, replacing damaged tissue. Researchers, such as Dr. Lola Reid, have identified biliary tree stem cells as potential pancreatic precursors, offering insights into diabetes treatment [2].
Conclusion
Research into adult stem cells has expanded our understanding of their therapeutic potential in regenerative medicine. Their diverse sources—from neural tissues to the liver—provide avenues for developing treatments without the ethical concerns associated with embryonic stem cells. With lower rejection rates and higher differentiation capabilities, adult stem cells offer hope for effectively treating degenerative diseases in the future.
References
- MacKlis, Jeffrey D.; Magavi, Sanjay S.; Leavitt, Blair R. (2000). “Induction of neurogenesis in the neocortex of adult mice”. Nature 405 (6789): 951–5.
- Biliary Tree Stem Cells, Precursors to Pancreatic Committed Progenitors: Evidence for Possible Life-long Pancreatic Organogenesis – Link.
This structure enhances readability and SEO by incorporating targeted keywords like “adult stem cells,” “neural stem cells,” “hematopoietic stem cells,” and specific study references.
- Published in Corporate News / Blog
Global Stem Cells Group to Participate in the 15th International Congress of Aesthetic Surgery in Boca del Rio, Veracruz
More than 1,500 aesthetic surgeons and specialists in the fields of anti-aging and regenerative medicine from around the globe will attend the four day event.Charles Mahl, M.D. and David B. Audley will representGlobal Stem Cells Group, Inc. as keynote speakers at the 15th International Congress of Aesthetic Surgeryin Boca del Rio in Veracruz, Mexico July 9-12, 2015. Mahl, a member of the Global Stem Cells Group Scientific Advisory Board, and Audley, the chairman and general secretary of the Regentech Alliance (RTA), will join more than 1,500 aesthetic surgeons and specialists in the fields of anti-aging and regenerative medicine from around the globe for the four day event.
Hosted by the Instituto de Estudios Superiores en Medicina (Institute of Advanced Studies in Medicine) in Veracruz, conference attendees will include an international lineup of physicians and medical practitioners in a variety of disciplines who will gather to discuss the newest therapies, protocols and innovative procedures available in aesthetic medicine.
Mahl, who maintains an active practice in regenerative medicine, preventive aging and pain therapies, will bring his expertise in prolotherapy, platelet rich plasma injections and stem cell therapies to the conference. Audley is a pioneer in the field of regenerative medicine and the founding executive director of the International Cellular Medicine Society (ICMS), the first professional medical association dedicated to the development of standards and accreditation for medical facilities engaged in cell-based therapies.
The conference will feature workshops in botulinum toxin applications for beginners and advanced students, and peeling treatments for stretch marks. Some of the topics to be addressed at the event include updates in aesthetic surgery, regenerative medicine therapies, platelet rich plasma applications, clinical and therapeutic stem cell applications, facial fillings, COFEPRIS guidelines, legal issues associated with aesthetic surgery and more.
The conference will take place at the Hotel Galerias Plaza Veracruz, Blvd. Adolfo Ruiz Cortines #3495, Costa Verde, Boca Del Río, Veracruz. For more information on the 15th International Congress of Aesthetic Surgery, visit the Global Stem Cells Group website, email bnovas(at)stemcellsgroup(dot)com or call 305-560-5337.
About Global Stem Cell Group:
Global Stem Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators and solution providers with the shared goal of meeting the growing worldwide need for leading edge stem cell treatments and solutions. With a singular focus on this exciting new area of medical research, Global Stem Cells Group and its subsidiaries are uniquely positioned to become global leaders in cellular medicine.
Global Stem Cells Group is a publicly traded company operating under the symbol MSSV. https://finance.yahoo.com/quote/mssv/
About Charles Mahl, M.D.:
Charles F. Mahl, M.D. is a Miami-based specialist in regenerative medicine, preventive aging and pain therapies. His expertise includes prolotherapy, platelet rich plasma injections and stem cell therapies for a variety of painful orthopedic conditions and injuries involving (but not limited to) the back, sacroiliac joints, hips, knees, shoulders and neck. Mahl’s background as a vitreo-retinal surgeon prior to his training in regenerative medicine makes him eminently qualified to perform stem cell therapies on the eyes.
A member of the Global Stem Cells Group Scientific Advisory Board, Mahl sees stem cell therapies as medicine’s new frontier, offering unlimited possibilities for easing and eliminating many forms of disease and injury-related pain. He is licensed to practice medicine in Florida and Board Certified in Integrative Medicine. Mahl has completed multiple fellowships in age management medicine, and spent more than two years in a mentorship program for prolotherapy and regenerative injection medicine with Alvin Stein, M.D., a relationship that continues to this day. For Mahl’s full bio, visit http://www.stemcellsgroup.com/advisory-board/.
About David B. Audley:
David B. Audley serves as the Chair and General Secretary of the Regentech Alliance (RTA), a 501(c)3 backed by individuals and institutions who support the Regentech mission to bring peer oversight and transparency to the field of cell-based and regenerative medicine. Audley is a pioneer in the emerging field of regenerative medicine, and the founding executive director of the International Cellular Medicine Society (ICMS), the first professional medical association dedicated to the development of standards and accreditation for medical facilities engaged in cell-based therapies. Audley has taken a leadership role in drafting international standards and governmental regulations for the Cayman Islands and the Bahamas, and has worked with regulators in Mexico, the Kingdom of Jordan, and China to provide frameworks for physicians. Audley is a well-known lecturer who has spoken widely on varying topics dealing with the trends in patient care, the importance of oversight for investigational therapies, the emergence of regenerative medicine and the global and regulatory issues associated with medical tourism. For more information, visit http://regen-tech.org.
- Published in Press Releases
Global Stem Cells Group, Stem Cell Training and Anti-aging Medicine Specialist John P. Salerno, M.D. to Hold Training Course in Manhattan
The course will focus on stem cell therapies for a variety of conditions and treatments including anti-aging therapies.MIAMI (PRWEB) June 08, 2015
Global Stem Cells Group and its subsidiary Stem Cell Training, Inc. have announced plans to conduct a hands-on, two day intensive stem cell training course for physicians and qualified medical professionals Sept. 18 -19, 2015. The training course will be led by anti-aging specialist John P. Salerno, M.D. in Midtown Manhattan.
The founder of The Salerno Center, Salerno practices integrative medicine, combining traditional and alternative healing methods. The course will focus on stem cell therapies for a variety of conditions and treatments including anti-aging therapies. Salerno trained in anti-aging medicine and has opened more than 20 anti-aging medical centers worldwide, including 10 in Japan, three in Brazil and two in Korea.
The Adipose and Bone Marrow Stem Cell Training Course was developed for physicians and high-level practitioners to learn the process through an intensive, hands-on training session that arms participants with clinical protocols and state-of-the-art techniques for isolating and re-integrating adipose- and bone marrow-derived stem cells.
The objective of the training is to teach effective regenerative medicine techniques that can be used to treat patients in-office.
Global Stem Cells Group’s Stem Cell Training, Inc. courses have been extended to approximately 35 countries, allowing a global community of physicians to learn how to apply these new stem cell technologies.
For more information, visit the Stem Cell Training, Inc. website, email info(at)stemcelltraining(dot)net, or call 305-560-5337.
About Global Stem Cells Group:
Global Stem Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators and solution providers with the shared goal of meeting the growing worldwide need for leading edge stem cell treatments and solutions.
With a singular focus on this exciting new area of medical research, Global Stem Cells Group and its subsidiaries are uniquely positioned to become global leaders in cellular medicine.
Global Stem Cells Group’s corporate mission is to make the promise of stem cell medicine a reality for patients around the world. With each of GSCG’s six operating companies focused on a separate research-based mission, the result is a global network of state-of-the-art stem cell treatments.
Global Stem Cells Group is a publicly traded company operating under the symbol MSSV. https://finance.yahoo.com/quote/mssv/
About Stem Cell Training, Inc.:
Stem Cell Training, Inc. is a multi-disciplinary company offering coursework and training in 35 cities worldwide. Coursework offered focuses on minimally invasive techniques for harvesting stem cells from adipose tissue, bone marrow and platelet-rich plasma. By equipping physicians with these techniques, the goal is to enable them to return to their practices, better able to apply these techniques in patient treatments.
The company’s training courses are designed to make the best use of stem cell technology available to treat various diseases in a manner that is accessible to everyone. Stem Cell Training, Inc.’s mission is to introduce the promising world of cellular medicine to everyone who can benefit from its application, and to provide high quality, effective and efficient training that complies with the highest medical standards to physicians worldwide.
About John P. Salerno, M.D.:
The go-to doctor for professional, comprehensive and full-service care, John P. Salerno, M.D. offers life-changing health solutions and educates both patients and physicians on the benefits of health, wellness and complementary medicine with a specialized focus in vitamin IV therapy, heavy metal detox, weight loss, anti-aging medicine, allergies and hair loss. A former partner of the late Robert C. Atkins, M.D. of “The Atkins Diet” fame, Salerno created and developed his own award-winning diet called “The Silver Cloud Diet,” launching a worldwide movement for patients and physicians to grow, heal, and learn.
Salerno’s cutting-edge medical approach incorporates observation and state-of-the-art testing, enabling him to pioneer an exclusive treatment plan that is restorative and beneficial. Salerno is the author of two top-selling diet and lifestyle books,“Fight Fat with Fat” and “The Salerno Solution,” as well as a popular lecturer, radio host and global media icon.
- Published in Press Releases
Global Stem Cells GroTurkeyup subsidiary Stem Cell Training Announces First Training Course to Take Place in Turkey
Global Stem Cell Training, Inc. announces plans to conduct the first stem cells harvesting and reintegration training course in Turkey Sept. 15 and 16, 2015. The training course will be held in Istanbul and lead by world renowned plastic surgeon Tunc Tiryaki, M.D.
Global Stem Cells Group and its subsidiary Stem Cell Training, Inc. have announced plans to conduct Turkey’s first ever stem cell
Tunv Tryak, M.D.
harvesting and reintegration course Sept 15 and 16, 2015. Through his alliance with Stem Cell Training, Inc. and in conjunction with medical device manufacturer Marina Medical, Tunc Tiryaki, M.D. will conduct the Adipose and Bone Marrow Stem Cell Training Course for medical professionals in Istanbul.
Tiryaki, a renowned plastic surgeon practicing in London and Istanbul, is a pioneer in cell enriched fat transfer. The course will focus on stem cell therapies for cosmetic/aesthetic conditions.
The Adipose and Bone Marrow Stem Cell Training Course was developed for physicians and high-level practitioners to learn the process through an intensive, hands-on training session to arm participating physicians with clinical protocols and state-of-the-art techniques for isolating and re-integrating adipose- and bone marrow-derived stem cells.
The objective of the training is to bridge the gap between bench science in the laboratory and the doctor’s office by teaching effective, in-office regenerative medicine techniques.
Global Stem Cells Group’s Stem Cell Training, Inc. courses have been extended to approximately 35 countries, allowing a global community of physicians to learn how to apply these new stem cell technologies.
For more information, visit the Stem Cell Training, Inc. website, email info(at)stemcelltraining(dot)net, or call 305-560-5337.
About Global Stem Cells Group:
Global Stem Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators and solution providers with the shared goal of meeting the growing worldwide need for leading edge stem cell treatments and solutions.
With a singular focus on this exciting new area of medical research, Global Stem Cells Group and its subsidiaries are uniquely positioned to become global leaders in cellular medicine.
Global Stem Cells Group’s corporate mission is to make the promise of stem cell medicine a reality for patients around the world. With each of GSCG’s six operating companies focused on a separate research-based mission, the result is a global network of state-of-the-art stem cell treatments.
Global Stem Cells Group is a publicly traded company operating under the symbol MSSV. https://finance.yahoo.com/quote/mssv/
About Stem Cell Training, Inc.:
Stem Cell Training, Inc. is a multi-disciplinary company offering coursework and training in 35 cities worldwide. Coursework offered focuses on minimally invasive techniques for harvesting stem cells from adipose tissue, bone marrow and platelet-rich plasma. By equipping physicians with these techniques, the goal is to enable them to return to their practices, better able to apply these techniques in patient treatments.
The company’s training courses are designed to make the best use of stem cell technology available to treat various diseases in a manner that is accessible to everyone. Stem Cell Training, Inc.’s mission is to introduce the promising world of cellular medicine to everyone who can benefit from its application, and to provide high quality, effective and efficient training that complies with the highest medical standards to physicians worldwide.
###
- Published in Press Releases
Global Stem Cells Group Announces First Stem Cell Training Course to Take Place in Romania
Stem Cell Training, Inc., a subsidiary of Global Stem Cells Group, announces plans to conduct the first stem cell training course in Romania Nov. 27-28, 2015. The training class will be held in Bucharest and lead by Cosmetic Surgeon Morad Iancu, M.D.
Global Stem Cells Group and its subsidiary Stem Cell Training, Inc. have announced plans to conduct Romania’s first ever stem cells harvesting and reintegration course Nov. 27-28, 2015. Through an alliance with Miami-based Stem Cell Training, Inc., Cosmetic Surgeon Morad Iancu, M.D. will conduct the Adipose and Bone Marrow Stem Cell Training Course for medical professionals in Bucharest.
Iancu is a reconstructive plastic surgery specialist practicing in Bucharest and Tel Aviv, Israel, and a popular “celebrity doctor” in Eastern Europe.
The Adipose and Bone Marrow Stem Cell Training Course was developed for physicians and high-level practitioners to learn the process of isolating and re-integrating adipose- and bone marrow-derived stem cells through an intensive, hands-on training session. The objective is to arm participating physicians with clinical protocols and state-of-the-art regenerative medicine techniques so that they can bring regenerative medicine therapies to their patients in-office. Iancu will focus the training session on stem cell treatments in cosmetic applications.
Global Stem Cells Group’s Stem Cell Training, Inc. courses have been extended to approximately 35 countries, allowing a global community of physicians to learn how to apply these new stem cell technologies.
For more information, visit the Stem Cell Training, Inc. website, email info(at)stemcelltraining(dot)net, or call 305-560-5337.
About Global Stem Cells Group:
Global Stem Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators and solution providers with the shared goal of meeting the growing worldwide need for leading edge stem cell treatments and solutions.
With a singular focus on this exciting new area of medical research, Global Stem Cells Group and its subsidiaries are uniquely positioned to become global leaders in cellular medicine.
Global Stem Cells Group’s corporate mission is to make the promise of stem cell medicine a reality for patients around the world. With each of GSCG’s six operating companies focused on a separate research-based mission, the result is a global network of state-of-the-art stem cell treatments.
Global Stem Cells Group is a publicly traded company operating under the symbol MSSV. https://finance.yahoo.com/quote/mssv/
About Stem Cell Training, Inc.:
Stem Cell Training, Inc. is a multi-disciplinary company offering coursework and training in 35 cities worldwide. Coursework offered focuses on minimally invasive techniques for harvesting stem cells from adipose tissue, bone marrow and platelet-rich plasma. By equipping physicians with these techniques, the goal is to enable them to return to their practices, better able to apply these techniques in patient treatments.
The company’s training courses are designed to make the best use of stem cell technology available to treat various diseases in a manner that is accessible to everyone. Stem Cell Training, Inc.’s mission is to introduce the promising world of cellular medicine to everyone who can benefit from its application, and to provide high quality, effective and efficient training that complies with the highest medical standards to physicians worldwide.
- Published in Press Releases
We may soon be able to heal autoimmune disorders with Stem Cells
Autoimmune disorders are conditions where the body’s immune system mistakenly attacks healthy cells, causing damage to tissues and organs. With over 80 known types, including diabetes type 1, lupus, rheumatoid arthritis, celiac disease, and multiple sclerosis, these disorders affect millions worldwide.
Understanding Autoimmune Disorders
The exact causes of autoimmune disorders remain unclear, though triggers like viruses, bacteria, or certain medications may disrupt immune function, leading the body to attack its own tissues. Common targets include red blood cells, skin, connective tissues, blood vessels, and various glands.
Current Treatments and Limitations
Standard treatments for autoimmune disorders primarily involve immune-suppressing medications, which offer temporary relief but do not provide a cure. Researchers are therefore exploring alternative approaches, such as stem cell therapy, to address these conditions effectively.
The Use of Stem Cells in Autoimmune Disorders
Mesenchymal Stem Cells (MSCs) in Immunomodulation
Research indicates that mesenchymal stem cells, derived from sources like bone marrow, exert immunological functions that help maintain immune balance. Studies, including one published in Arthritis Research and Therapy, highlight MSCs’ ability to regulate immune responses and potentially prevent tissue destruction [1].
Hematopoietic Stem Cells (HSCs) for Severe Autoimmune Diseases
Studies, such as those conducted at Harvard Medical School, explore the use of hematopoietic stem cells in treating severe autoimmune diseases like rheumatoid arthritis and multiple sclerosis. Transplantation of HSCs following immunosuppressive therapies has shown promise in achieving disease remission [2].
Neural Stem Cells (NSCs) in Multiple Sclerosis
In multiple sclerosis research, neural stem cells derived from the central nervous system demonstrate neuroprotective and immunomodulatory effects. Studies suggest these cells could potentially repair damaged nerve tissues and improve symptoms in MS patients [3].
Mesenchymal Stem Cells (MSCs) in Rheumatoid Arthritis
Research on rheumatoid arthritis indicates that mesenchymal cells derived from sources like the placenta possess immunosuppressive properties. Studies, such as those investigating human amnion mesenchymal cells, show promise in alleviating arthritis symptoms and reducing disease severity [4].
Challenges and Future Directions
Despite promising results, challenges remain in optimizing stem cell therapies for autoimmune disorders. Researchers must establish precise protocols and address issues like immune rejection and treatment efficacy in larger clinical settings.
References
- Published in Corporate News / Blog
Stem Cell Training, Inc. Announces First European Symposium on Cellular and Regenerative Medicine
Global Stem Cells Group and its subsidiary Stem Cell Training announce the company’s first European symposium on cellular and regenerative medicine, to be held in Barcelona, Spain Oct. 9-10, 2015. The symposium will be hosted at the Official Medical College Of Barcelona by J. Victor Garcia Gimenez, M.D., of Therapeutic Confrontations.
Share on TwitterShare on FacebookShare on Google+Share on LinkedInShare on PinterestEmail a friend
stem cell therapies,EuroMedicom,stem cell medicine,global stem cells group,medical tourism,cellgenic,
Stem Cell Training
We have put together a program designed to include cellular communication pathways, influence of the niche in stem cell behavior, and recent studies and supporting investigational protocols for clinical applications.
Miami, FL (PRWEB) May 26, 2015
Global Stem Cells Group and Stem Cell training, Inc. have announced plans for the company’s first cellular and regenerative medicine symposium in Barcelona Spain Oct. 9, 2015, followed by a full day, hands-on stem cell training class Oct. 10. The event will be hosted by J. Victor Garcia Gimenez, M.D., President of Therapeutic Confrontations (CONFTERA) in Barcelona.
In response to the medical community’s increasing interest in regenerative medicine and recent advances in cellular therapies, Global Stem Cells Group, CONFTERA, and their faculties have put together a program designed to include cellular communication pathways, influence of the niche in stem cell behavior, and recent studies and supporting investigational protocols for clinical applications. Theory portions of the symposium will be dictated by relevant members of both faculties.
The symposium will be followed by a full day, hands-on training session on Oct. 10 to provide participating physicians with state-of-the-art techniques for isolating and re-integrating adipose- and bone marrow-derived stem cells, along with clinical protocols.
The symposium will be held in the auditorium of the Official Medical College Of Barcelona.
For more information, visit the Global Stem Cells Group website or the Stem Cell Training, Inc. website, email bnovas(at)stemcellsgroup(dot)com, or call 305-560-5337,
About Global Stem Cells Group:
Global Stem Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators and solution providers with the shared goal of meeting the growing worldwide need for leading edge stem cell treatments and solutions.
With a singular focus on this exciting new area of medical research, Global Stem Cells Group and its subsidiaries are uniquely positioned to become global leaders in cellular medicine.
Global Stem Cells Group’s corporate mission is to make the promise of stem cell medicine a reality for patients around the world. With each of GSCG’s six operating companies focused on a separate research-based mission, the result is a global network of state-of-the-art stem cell treatments.
Global Stem Cells Group is a publicly traded company operating under the symbol MSSV. https://finance.yahoo.com/quote/mssv/
About Stem Cell Training, Inc.:
Stem Cell Training, Inc. is a multi-disciplinary company offering coursework and training in 35 cities worldwide. Coursework offered focuses on minimally invasive techniques for harvesting stem cells from adipose tissue, bone marrow and platelet-rich plasma. By equipping physicians with these techniques, the goal is to enable them to return to their practices, better able to apply these techniques in patient treatments.
The company’s training courses are designed to make the best use of stem cell technology available to treat various diseases in a manner that is accessible to everyone. Stem Cell Training, Inc.’s mission is to introduce the promising world of cellular medicine to everyone who can benefit from its application, and to provide high quality, effective and efficient training that complies with the highest medical standards to physicians worldwide.
About J. Victor Garcia Gimenez, M.D. and CONFTERA:
J. Victor Garcia Gimenez, M.D., President of Therapeutic Confrontations (CONFTERA), is a specialist in orthopedic surgery and practices cosmetic medicine and surgery, anti-aging medicine, and esthetic therapies in Barcelona.
Garcia Giminez received a Bachelor of Medicine and Surgery degree from the Autonomous University of Barcelona in 1977, and a Specialist in Orthopedic Surgery degree in 1980, also from the Autonomous University of Barcelona. He later received a diploma in Cosmetic Medicine and Surgery from the Autonomous University of Barcelona before attending the National College of Medicine and Aesthetics (Collège National de Médecine et Esthetique) in Montlhéry, France. Garcia Giminiz received a master’s degree in Dermopharmacy and Cosmetology at the University of Barcelona, and a training diploma in Cosmetic Medicine and Surgery at the Medical College of Barcelona; he received a Master’s degree in Cosmetology, Esthetic Medicine and physiological aging from the University of Barcelona.
Garcia Giminiz is the President of the Spanish Society of Medicine and Cosmetic Surgery; Co-director of the UAB-SEMCC; Chairman for Spain of the International Academy of Cosmetic Surgery and a number of additional medical and professional boards.
- Published in Press Releases
STANFORD RESEARCHERS ISOLATE SKELETAL STEM CELLS THAT GIVE RISE TO BONES AND CARTILAGE
Stanford Researchers Isolate Skeletal Stem Cells That Give Rise to Bones and Cartilage
Cartilage and bone deterioration often result from aging, lifestyle factors, or injuries. Unlike bone tissue, mature cartilage has limited self-healing capabilities. Surgical interventions like joint replacement are costly and carry risks such as rejection and infection [1].
Stanford’s Breakthrough in Tissue Engineering
In January 2015, Stanford University School of Medicine scientists made a significant breakthrough in tissue engineering. They successfully isolated skeletal stem cells (myoblasts) capable of generating bone and cartilage in mice. This achievement included mapping the chemical signals crucial for directing stem cell differentiation [2].
Understanding Skeletal Stem Cells
Stem cells are undifferentiated cells with the ability to develop into specialized cell types, replenishing damaged tissues. While embryonic stem cells (ESCs) are pluripotent and controversial due to ethical concerns, adult stem cells from sources like bone marrow and adipose tissue are promising alternatives. Recent research suggests that adult stem cells may differentiate into diverse cell types beyond their tissue of origin.
Stanford’s Research Insights
Stanford’s study focused on rapidly dividing cells found at the ends of mouse bones. Human skeletal muscle-derived cells transplanted into mice showed remarkable regenerative potential after irradiation and cryoinjury preconditioning. This research not only reconstructed bone tissues but also mapped the developmental trajectory of skeletal stem cells.
Irving Weissman, MD, director of the Stanford Institute for Stem Cell Biology and Regenerative Medicine, anticipates these findings will advance human therapies for cartilage and bone regeneration [3].
Differentiation and Therapeutic Applications
Skeletal stem cells contribute to bone formation, adipocyte production (fat cells), and cartilage regeneration. Their potential therapeutic applications extend to treating muscular conditions like muscular dystrophy, joint disorders such as arthritis, and even autoimmune diseases like rheumatoid arthritis and multiple sclerosis.
Challenges and Future Prospects
Despite promising results, challenges in scaling up cell production remain a barrier to widespread clinical application of skeletal stem cell therapies.
References
- Development and Remodeling of Skeletal Tissue – David King, School of Medicine, Southern Illinois University, 2009
- Researchers Isolate Stem Cell That Gives Rise to Bones, Cartilage in Mice – Christopher Vaughan, Stanford Institute for Stem Cell Biology and Regenerative Medicine, 2015
- Stanford Stem Cell Research
- Genetic Control of Skeletal Development
- Published in Corporate News / Blog
PROTEINS PRODUCED BY STEM CELLS, USED IN BONE REGENERATION
Bone loss and weakening are natural effects of aging, beginning as early as age 30. Factors like smoking, inadequate calcium intake, certain medications, and hormonal changes accelerate bone resorption, leading to decreased density, porous bones, and increased fracture risk.
Stem Cell Innovations in Bone Reconstruction
Researchers at the Gladstone Institutes have pioneered a method using proteins derived from stem cells to stimulate bone reconstruction. Unlike traditional methods that rely on bone grafts from cadavers, this approach extracts bone-forming proteins directly from stem cells.
Advantages of Stem Cell Proteins
In experiments on mice, proteins extracted from stem cells were injected into muscle tissue, promoting significant bone growth without the risks associated with traditional bone grafts. This method shows promise for safer, more effective bone repair in humans, with lower rejection and tumor formation risks [1].
Scientific Validation and Clinical Applications
A study published in Scientific Reports affirmed that stem cell-derived proteins offer a reliable source for tissue regeneration. This builds on earlier research, such as Dr. Ranieri Cancedda’s pioneering work using bone marrow cells to repair bone defects [2].
Cutting-Edge Research and Future Directions
Researchers at the National Institutes of Health successfully grew new bone from stem cells derived from skin cells, published in Cell Reports. By reprogramming skin cells into induced pluripotent stem cells (iPSCs) and differentiating them into bone cell precursors, they achieved bone growth in primates without tumor formation. This method harnesses the immune compatibility and versatility of iPSCs, heralding new possibilities for personalized bone regeneration [3].
Conclusion
While the use of stem cells in bone regeneration is advancing, ongoing research aims to refine techniques for optimal integration and long-term effectiveness in human patients.
References
- Published in Corporate News / Blog
