For most women, a tiny pimple on the face is enough to ruin their day. Or week. Even the slightest imperfection that may have a 1% chance of getting noticed by others will freak them out. For these women, Melasma is their darkest nightmare. It’s a pretty common issue, a result of exposure to sun, that causes brown patches on the face. Permanent patches, I should add.

If you’re suffering from Melasma, the road to “recovery” usually looks like this.

  1. You hope that it’ll fade away.
  2. Your friend suggests you try apple cider vinegar and lemon juice treatment.
  3. Slightly disappointed.
  4. You visit a dermatologist who’ll prescribe a bleaching cream (hydroquinone or similar).
  5. Full-on disappointment.
  6. You Google the hell out of the topic.
  7. Overwhelm.
  8. Concealers and makeup becomes your best friend.

At this point, no one can convince you there is a treatment for getting rid of melasma. Trying more and more treatment only runs the risk of making the condition worse. So what would you do?

Platelet-Rich Plasma For Melasma

What about Platelet-Rich Plasma For Melasma?

According to recent Turkish and Malaysian studies, Platelet-Rich Plasma is showing great promise for melasma. The one good thing about PRP for Melasma is the fact that PRP won’t make the condition worse unlike IPL, fraxel or other treatments. So that’s one of the treatment you can confidently try without worry. It’s like getting a natural facial treatment that has a whole lot of potential benefits even if it didn’t help cure melasma.

PRP injections work by supplying growth factors to reduce the pigmentation. And being an independant treatment with no downtime, it can be done in conjunction with conventional treatments for melasma to add and enhance the effects. There are more than 30 bioactive substances in Platelet-Rich Plasma that has separate roles like increasing skin volume and adding new blood vessels to name a few.

Platelet-Rich Plasma with Microneedling

This is the most common combination for Platelet-Rich Plasma therapy. Here’s a video of Dr. Michael Somenek performing PRP injection on a patient of his immediately after microneedling. The combination is known to have produced results for a lot of varieties of skin pigmentation issues that it’d not be wise for anyone to ignore it for melasma, especially when creams and peels didn’t help. More important is PRP’s ability to stimulate collagen production in the area so it tightens the pores and makes your skin glowing.

Why Platelet-Rich Plasma?

PRP is primarily a healing vehicle. It needs to be injected into the membrane below the skin. The way it works is by supplying the underlying skin membrane with collagen and tenascin stimulated by the transforming growth factors in PRP. These growth factors also promote formation of new blood vessels that in some cases results in disappearance of spider veins.

The released growth factors (mainly platelet derived growth factor (PDGF), epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF) and transforming growth factor-beta (TGF-ß)) can stimulate proliferation of fibroblast and epidermal cell, and collagen synthesis. In addition, the transforming growth factor-beta (TGF-ß) has been proven to inhibit melanogenesis — or reverse skin pigmentation — the exact opposite effect of exposure to UV-B radiation.

Typically, patients see excellent results with 2-3 PRP injections in the first 3 months. And clinical studies have shown that it will maintain after 6 months.

However, Melasma is known to recur even after successful treatments. So you must take precautions against it by using sunscreen with broad-spectrum protection and an SPF of 30 or higher. And avoid skin care products that are harsh as they can exacerbate melasma.


Platelet-Rich Plasma has a proven record for healing soft-tissues and other living tissues. But can it actually heal the bones itself?

This could mean PRP, when applied to an affected area whether it’s an elbow joint or knee or back bone area, actually heals everything within it’s reach including the bones. Is that really why PRP actually works?

Let’s examine.

Platelet-Rich Plasma For Bone Healing

Bones are not just lifeless matter attached to living tissues. It’s as much living as the tissues themselves. And just like the tissues, it’s constantly changing too. The old bone cells are broken down and replaced with new ones in a three-part process called bone remodeling the involves resorption (digestion of old bone cells), reversal (new cells are birthed) and formation (new cells turn into fully formed bones).

This process, just like any other biological processes in the body, requires hormones and growth factors. Some of the names include parathyroid hormone (PTH), calcitriol, insulin-like growth factors (IGFs), prostaglandins, tumor growth factor-beta (TGF-beta), bone morphogenetic proteins (BMP), and plain old cytokines. For this discussion we need to remember only one thing: a large cytokines and growth factors are involved in bone remodeling process.

Which means we accelerate the bone remodeling process by supplying these cytokines and growth factors as suggested by studies like this, this, this, this, this and this.

Why Platelet-Rich Plasma?

Autologous Platelet-Rich Plasma (PRP), being completely “whole and natural” can more closely simulate a highly efficient in-vivo situation that anything else out there that are made up of artificial recombinant proteins. In PRP, we are taking advantage of the biological benefits of growth factors whose functions we know as well as those we do not know of yet. From the 15+ factors we know are in PRP including platelet derived growth factor (PDRF), transforming growth factor-beta (TGF-beta), platelet factor 4 (PF4), interleukin 1 (IL-1), platelet-derived angiogenesis factor (PDAF), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), platelet-derived endothelial growth factor (PDEGF), epithelial cell growth factor (ECGF), insulin-like growth factor (IGF), osteocalcin (Oc), osteonectin (On), fibrinogen (Fg), vitronectin (Vn), fibronectin (Fn) and thrombospontin-1 (TSP-1)… we’re actually supplying a “holistic” set of nutrients for healing that cannot be mimicked by those obtained artificially.

Platelet-Rich Plasma For Bone Healing

Organic Fertilizers For The Body

The PRP difference is like adding chemical fertilizers versus organic fertilizers on plants. Chemical fertilizers are rich in essential nutrients that we know are needed for crops. On the other hand, organic fertilizers supply nutrients not only to the plants but also to the soil, improving the soil structure and tilth, water holding capacity, reduces erosion as well as promote slow and consistent release of nutrients to the plants itself.

Clearly, organic fertilizers are better, aren’t they?

Platelet-Rich Plasma are like organic fertilizers for our body.

Bonus: Strong Antimicrobial Properties

It seems that the Platelet-Rich Plasma’s healing function has synergistic function to anti-microbial properties. A new study confirms that using Platelet-Rich Plasma in surgeries may have the potential to prevent infection and to reduce the need for costly post-operative treatments.

That’s a nice bonus for the organic fertilizer of our bodies. Perhaps, there are more. So why wouldn’t anyone not take advantage of them?

The scope of Platelet-Rich Plasma is growing as the scientific community continues to unearth its inherent properties. PRP is an unignorable, and unavoidable component of healing.

To understand why stem cell platelet-rich plasma or co-transplantation of Adipose-derived mesenchymal stem cells and PRP, is such a remarkable idea in regenerative medicine, let’s spend a little time looking at the mechanics of PRP.

Platelet-Rich Plasma’s Role As Repairmen

The one thing that makes Platelet-Rich Plasma a hero in several fields (if not all) of medicine is the fact that the diverse growth factors in it are able to stimulate stem cell proliferation and cell differentiation (the factors that determine effective tissue regeneration and healing) on any part of the body.

These growth factors are abundant in the blood and act as the natural repairmen of tissues.

In the perfect scenario, there’s plenty of blood flow to every part of the body and these “repairmen” are always on-call to address any healing needs that may arise. However, if the injured area has a poor blood supply — especially areas that are constantly move like tendons, ligaments and joints — demand for these repairmen can outgrow supply. Meaning, healing (or regeneration of tissues) is put on hold till further repairmen are available.

The train of Platelet-Rich Plasma then arrives with enough of these repairmen to warrant resumption of healing.

There’s another part of this picture we haven’t talked about so far: stem cells.

As far as Platelet-Rich Plasma and it’s growth factors are concerned, they are mere repairmen. They can’t do the work by themselves. They need the basic raw materials to work with. And that raw material here is the stem cells.

Stem cells are the ones actually being regenerated to form new tissues for healing.

Stem Cells As The Raw Materials For PRP

Stem cells are the only raw materials that PRP works with for regeneration. These are like the fundamental building blocks of all other cells. These cells can be can be guided into becoming specialized cells under the right conditions.

In addition, they can also divide themselves to form new stem cells or new specialized cells.

So for Platelet-Rich Plasma to work well, it needs to be applied to an area with lots of stem cells like the heart, liver, blood vessels etc. Incidentally Platelet-Rich Plasma’s healing properties were first discovered by cardiac surgeons who played with concentrated blood for faster healing of heart after surgery and it showed tremendous promise because stem cells are abundant in heart tissues.

But what if healing is needed in an area where there are not much stem cells?

With the new developments in stem cell technology that can be solved too. Because now we can supply the stem cells to areas where there are less like the joints, ligaments and tendons. For this, scientists usually use “mesenchymal stem cell” or MSCs. These are cells isolated from stroma and can differentiate to form adipocytes, cartilage, bone, tendons, muscle, and skin.

The most easiest way is to harvest it from adipose tissue or fat that we call Adipose-derived mesenchymal stem cells or ADSC.

Stem Cell Platelet-Rich Plasma

Supplying Both PRP And Stem Cells For Regeneration

In regions with hypoxia (poor blood supply) like joints, meniscus tissue, rotator cuff, spinal discs etc the supply of platelets (and therefore growth factors) as well as the stem cells are limited. So what if we supplied both the stem cells and Platelet-Rich Plasma for triggering the regeneration process?

That’s the question these Japanese scientists answered in their research. Here’s another group of scientists who took on the same challenge.

They used Adipose-derived mesenchymal stem cells (ADSC) which is known for their ease of isolation and extensive differentiation potential. These researchers noted that these stem cells often can’t survive in areas of local hypoxia, oxidative stress and inflammation – thereby making them ineffective. However, when Platelet-Rich Plasma (or thrombin-activated PRP) is added to ADSC, it kept them alive for prolonged periods and the growth factors in the Platelet-Rich Plasma triggered cell differentiation and proliferation more easily.

Why This Exact Combination Is The Future

Done this way, both Adipose-derived mesenchymal stem cells (ADSC) and Platelet-Rich Plasma are raw materials for healing that’s already available in plenty in almost every one (there are exceptions of course). That means, for complete healing to take place this combination treatment, still in it’s very primitive stage of development, may have the potential to replace expensive synthetic drugs that carry complex unexplained side effects. The procedure takes our body’s natural healing agents — stem cells from body fat and PRP from blood — and then inject it inside knee or other joints (or other areas where they are insufficient) for regeneration.

Isn’t that like the most wonderful thing ever?

Whether it’s cartilage cell, or a bone cell, or a collagen cell for ligaments and tendons that needs to be healed, all you need is a same-day procedure by a local, but specialized doctor, using the natural ingredients of the body.

I believe this special combo is a huge win for Platelet-Rich Plasma.

The Challenges For Growing Adoption Of This Treatment

We know Platelet-Rich Plasma has safe, yet high-speed recovery potential with it’s multiple growth factors. And it is effective in regenerative healing of cartilage injuries – the most toughest injuries to heal – as well as Osteoarthritis. However the challenges are Platelet Quality. We need to somehow ensure the Platelet-Rich Plasma quality is uniform. Currently it varies from two to several fold above baseline concentration based on donor’s physical condition.

Next we need to identify the exact PRP growth factors that promote ADSC proliferation. Scientists believe growth factors such as basic fibroblast growth factor (bFGF), epidermal growth factor, and platelet-derived growth factor stimulate stem cell proliferation while some growth factors under certain conditions are known to inhibit the process.

The percentage of PRP matters too. 5 percent, 10 percent, 15 percent and 20 percent Platelet-Rich Plasma in ADSC are tested by scientists.

The Only Treatment In Modern Medicine For Cartilage Regeneration

The bottom line is that Stem Cell Platelet-Rich Plasma or ADSC + PRP procedure is the only treatment in modern medicine that has showed cartilage regeneration. So it’s too important to ignore. And it could one of greatest advances that science has brought to the millions of people suffering from serious pain in their joints, knee and spine as well people suffering from all kinds of tendon diseases and injuries.


The time it takes to draw a patient’s blood, add a little citrate, and use a centrifugal machine with a PRP kit is only 15-20 minutes. This is the amount of time needed to create Platelet-Rich Plasma, or PRP. This can then be used for many purposes, using speeding up a patients recovery.

PRP is by far the best healing agent that has growth factors and platelets to help with the healing process, which is also completely free and natural to obtain.

What are The Advantages Of Using PRP Correctly?

It is easy to create PRP simpy by placing blood in a centrifuge, but it can have very little, if any, platelets, and would otherwise be useless. However, with the right equipment, you can make PRP with up to 7x the amount of platelets. This can be amplified by using fat tissue and collagen fibers to create a PRP matrix.

7 Popular PRP Treatments

  1. Facial Treatments

Many skin centers are thriving due to being one of the first to adopt PRP therapies. With the lack of side effects or down time, it became incredibly popular. These treatments include wrinkle reduction, skin rejuvenation, dark circle and bag erasure, rosacea treatment, and even lip augmentation.

One popular and generic treatment option includes combining PRP and a treatment known as microneedling. When this is applied, it’s effects are similar to facelifts, for far less cost and side effects.

  1. Hair Loss

PRP growth factors can be beneficial when it comes to reversing non-genetic early stage hair loss. Despite there being a huge market for this, almost no practitioners actually utilize it. Many clients have seen promise after hair thinning, and many have seen beard regrowth over time.

  1. Arthritis and Cartilage

Arthritis treatments alone cost patients 6.4 billion dollars in 2013 for the US alone, with projections of up to 9 billion by the end of the decade. However, unlike the other treatments, PRP is seen as the only treatment that can not just reduce symptoms, but also regrow the cartilage. One of the most popular examples would be treatments for Temporomandibulaar Joint Osteoarthritis.

  1. Anti-aging Properties

When it comes to the anti-aging market, there are a endless number of treatments and procures available. Yet, none of them even stand close to the effectiveness of PRP therapy. PRP combined with Microneedling can ve highly effective for strech marks, acne scars, breast augmentation, and even skin conditions like Lichen Sclerosus.

  1. Pain Relief and Musculoskeletal Healing

There are a ton of treatments in this category, with many of them being incredibly more effective than leading treatments. These include healing Rotator Cuffs, Tennis Elbow, Achilles Tendonitis, Patellar Tendonitis, Back Pain, Hip and Pelvic problems, Degenerative Disc Disease, Golfer’s Elbow, Labaral Tear, Brusitis, neck pain, avascular Necrosis, and even pain related to nerve regeneration.

Almost all of these treatment, as opposed to those in other categories on this list, also use ultrasound guidance when injecting the PRP directly into the affected tissue. This can allow patients to see fantastic results in as little as 2 weeks.

  1. Fertility

Ovarian Rejuvination is where PRP is injected directly into a woman’s ovaries. This is meant to help reverse menopause and help lower fertility issues. This treatment can even be used for sexual regeneration. Although similar, this treatment is not the same as other treatments where PRO is injected into the vagina, and is supposed to treat looseness, dryness, low sex drive, and incontinence.

  1. COPD (Chronic Obstructive Pulmonary Disease)

Allergies, asthma, and COPD are among the growing list of things that PRP is being used as a treatment for. For this to work, the PRP is mixed with a saline solution, and then, using a nebulizer, is inhaled, and helps to regenerate the lung tissue.

Although it can take up to 2 months for patients to see the effects, many are seeing improvements. Almost 1 million people suffer from COPD a year, so anything that can help treat the condition is beneficial.

The Future

PRP has been trending rather well in the recent years, and seems to be here for the long term. Not only it is a fully natural remedy, but it is one that works better than most or all traditional treatments. Many like it due to the fact that there are few side effects, it only takes a short amount of time, and there is no recovery period.

PRP has been adopted by thousands of clinics and practices throughout the US and the world. The demand for these treatments have been increasing almost faster than practices are choosing to provide them. Many patients are even willing to travel long distances just to receive these treatments.

So are you providing PRP treatments yet?

Since it is a new science, many people are skeptical about Platelet-Rich Plasma, otherwise known as PRP. There are some studies out there that state that PRP work no better than a similarly administered placebo, but there are many other studies and doctors that claim that PRP works and works well. This also works well at a much lower cost and less side effects, than traditional medicine.

One branch where the skepticism is loud and clear is podiatry, which deals with feet and ankles. Trying to combat this skepticism can help many surgeons to lower complication rates, improve patient satisfaction, and have better outcomes. For instance, here is a list of cases where PRP has been effective for the feet and ankles.

  1. Plantar Fasciitis

PRP has become rather common as a treatment for Plantar Fasciitis, with many studies to prove the efficacy of this treatment. For instance, Dr. Daanial Kassicieh or Sarasota Neurology claims that PRP is one of the most effective treatments for this condition, and that PRP is actually fully cure it. Many of his patients have avoided surgery just by utilizing PRP therapy.

This is done with no down time, no rehabilitation, and no side effects. This woud explain why plantar fasciitis is the 5th popular medical condition treated by PRP. This can be explained by over 3 million people that are diagnosed with this and no other treatment really works for it, besides, in fact, PRP.

  1. Archilles Tendonitis

This is another condition that can be fairly hard to treat, and gets worse over time unless healed. Many surgical approaches are often trickey and generally do not end up with good results. Because of this, the main treatment option is simply to give patients corticosteroids to reduce the pain, but really nothing else to treat the symptoms.

However, there have been many studies done that have shown that PRP is a lot more effective, including that from the European Foot and Ankle Society. This means that PRP is safer and more effective alternative than any other treatments available.

  1. Diabetic Foot Ulcers

Diabetic foot ulcers can be troublesome, especially when they do not heal or heal properly. Over 2.5 million Americans with diabetes who suffer from these ulcers. About 11% of these cases may need amputation of their affected limb. However, some studies have noted that just one injection of PRP and a topical solution bi-weekly started to heal the ulcers in just 8 weeks. Topical PRP also has been shown to work better than anti-septic creams as well.

  1. Regenerating Bones

Bone regeneration is most commonly needed in food and ankle area. Although mechanical stabilization works best, the utilization of PRP has been surprising. PRP helps with healing bones and soft tissue at the damage site. According to a recent systematic review of 64 articles, the conclusion was to include more PRP therapy into the healing of foot and ankle bones.

The science behind this is solid, for bone or tissue to form, three things are needed in the area:

  • A scaffold for the growth to take place
  • Biological stimulants to signal proteins
  • Stem cells that provide bone building potential

All three of these are crucial for bone formation.. PRP can provide at least two of these, so there is no reason to ignore it when it comes to bone regeneration.

  1. Ankle Sprains

This is an incredibly common condition, and can be effectively treated by using PRP therapy. In one randomized controlled trial, researchers studied the effects of PRP injections on athletes with ankle sprains. This study showed that not only did PRP reduce the healing time by 20 days, but that they also experienced much less pain. This can reduce the recovery period from 6 weeks, for just about 2 or 3 weeks.

Immobilization is Vital

When it comes to foot and ankle related injuries, one thing that really cannot be avoided in rest and rehabilitation. This is true regardless of whether PRP is administered. Because of this, many of the studies that shows PRP to be ineffective often don’t use rest and rehabilitation, and that alone can be an issue.

PRP is in no way a magic pill. All foot injuries need rest and rehabilitation in order to properly heal. With these two combined, it can drastically reduce healing times.

How can Foot and Ankle Surgeons Benefit?

Using PRP in foot and ankle injuries is not going anywhere, so utilizing it would be the best way to go. Test it out with your patients, and try using platelet-rich plasma therapy instead of simply prescribing pills or doing costly surgeries. Your patients will thank you in the end.

According to many physicians, PRP (Platelet-Rich Plasma) has been a lifesaver for their practice, while others claimed that it helped them become passionate about medicine again. This is because not only is it 100% from the body of the patient themselves, but it is also natural and comes with pretty much no side effects. It can also be used to treat a plethora of medical ailments, to the point where no other treatment options come close.

Although the above are all fantastic and solid reasons for offering PRP therapies, there are also a couple other reasons as well.

For instance, it is extremely simple compared to other treatment options. For about 1000$ as an initial investment, you can get started with offering PRP. The equipment is relatively cheap, and it pays for itself over a relatively short amount of time.

It also is not just a passing trend, as it has been going popular for a long time and shows no signs of slowing down. The market for PRP therapies is expected to reach almost 500 million dollars within the next 10 years, or an annual growth rate of 12.5% since 2015.

Patient satisfaction is another reason. In certain situations, the satisfaction rate for patients have been as high as 95%. This shocks many of the patients, who believe, although justifiably, that they cannot reverse or halt their condition without side effects, down time, and invasive surgeries.

The time for you to start including PRP into your practice is now, while the supply is low but the demand is booming. There is still a lot more promise when it comes to PRP as well, including combining PRP with other treatments to increase efficacy. Since no standard has yet to be established, you may be starting these standards yourself.

It is vital that we get more doctors to utilize PRP therapy so that they can be a pioneer in this field. PRP can turn medicine on its head, and missing out should not be a smart option.

The best part about it, is that PRP can be utilized in almost every field and specialty, from sports medicine, to pain management, skin rejuvenation, hair care, and even urology. Most of the physicians who utilize this treatment also saw higher patient retention rates as well.

So is there a legitimate reason to not add PRP to your practice?

A Guide To PRP Therapy

Many clients are highly skeptical that their ailments can get better just by utilizing a few injections. Many clients may quit after a few sessions, but then return when they feel their ailments easing up. This is especially true when it comes to the practice of Rheumatology.

Rheumatology has benefited immensely from the use of PRP, otherwise known as Platelet-Rich Plasma. This is because not only is it simple to administer, but it works wonders for musculoskeletal conditions, such as joint issues, swelling, and bone issues.

If you are a Rheumatologist, you have probably used, or at least heard, of PRP therapy. This has helped many patients from having to go through surgery. However, over 27 million Americans in the osteoarthritis segment alone would have benefited more if their rheumatologist used PRP therapy.

Not All Treatments Are Successful, Here Is Why

Sometimes PRP can work, sometimes it may not, and this can differ even among the same person. However, there are some things you can do to prevent treatments from failing.

  1. Concentration

For PRP to work, the platelets present in the blood extracted has to be more concentrated than the baseline in the body. This can work by utilizing a PRP kit, which you can purchase at Adimarket.  Using these kits, you can get a 5-8x the baseline, which works best for the treatments.

  1. White Blood Cells

PRP with white blood cells behave differently than those that do not have it. Most popular forms of PRP have these blood cells. There are three subgroups within this: Red Blood Cells, that don’t have platelets, Platelet Serum that has suspended platelets, and the Buffy Coat, which has both platelets as well as white blood cells. Adding in white blood cells can help speed up the healing process by removing bacteria and dead or dying cells.

  1.  Using Anti-Coagulants

When making PRP, it is standard to use an anti-coagulant. This prevents the blood from clotting, but it does make the blood a little more acidic than usual. This can be detrimental on the growth factors, so adding a buffer before injection can be beneficial.

The Growth Factors Used

PRP heals wounds rather well due mostly to the growth factors that re found in blood platelets. By activating these platelets, the growth factors are able to be used by tissues and ligaments. Although the specifics are not well known, there is plenty of evidence that growth factors help with inflammation, remodeling, and even regenerating cells.

What is the clinical Evidence supporting PRP?

  1. PRP and Subacromial Tendonitis.

PRP has been shown to be effective in treating Subacromial Tendonitis in many studies. One study, headed by Dr. Turlough O’Donnell of the UPMC Beacon Hispital in Dublin Ireland, studied 102 patients treated with PRP while another 102 were treated with a 20mL solution of bupivacaine and 80 mgs of methylprednisolone.

After 12 months of follow-up, the PRP group were 16 times less likely to have to have invasive surgery as opposed to the other group.

  1. Epicondylitis

This is often a chronic form of tendinopathy, and treatments are rarely effective. However, studies involving PRO have been promising. In one study, 19 patients who would otherwise have gotten surgery were given PRP treatment instead, and after 8 weeks, they saw a 60% improvement, and within two years, that number rose to 93%.

Another randomized double-blind study compared PRP with corticosteroids in 100 patients with chronic epicondylitis. The beneficial effects of PRP far outweighed the effects of the corticosteroids.

  1. Plantar Fasciitis

Otherwise known as Policeman’s Heel, plantar fasciitis is fairly common in the field of rheumatology. The main treatment to date would be to simply mask the symptoms by using corticosteroids. However, one study showed that PRP was much better than corticosteroids after a 3 month followup.

  1. Knee Osteoarthritis

PRP therapies for osteoarthritis of the knee have been studies intensively in the past few years. These studies have shown a lot of promise for this therapy. One systematic review showing a total of 1543 participants showed that PRP therapy fares better than hyaluronic acid when it comes to improving knee joint cartilage.

How PRP can Benefit Rheumatology

PRP is not just a passing trend, and is here to stay, and may be the most useful tool for rheumatologists. With no other treatments coming close to its safety, efficacy, or simplicity, It is a shame that it is not more common than it currently is. Since this therapy carries no risk, there is no reason to at to not at least give it a try.

Trying it is relatively inexpensive, and will pay for itself over time. Adimarket will be happy to supply you with kits, and even a standard lab centrifuge.

We need more rhumatologists to utilize PRP and help patients forgo intrusive surgeries. This will be beneficial for over 27 million Americans. Besides, since it is a new treatment option, getting into the field early will make you a pioneer in the field, which will benefit your practice immensely.



Thousands of skincare centers across the nation provide at the very least one kind of PRP treatment. However, most do not go any farther than micro-needling with a topical solution. This is mainly because it is far simpler than all other methods, and it is incredibly popular. However, it would make more sense to many practices who have invested in equipment for add in PRP injections as well.

PRP Is Growing Substantially

Regardless of what is being treated, the protocol for obtaining PRP is the same: You draw the blood, place it in the centrifuge, and then take out the PRP from the rest of the material. This simplicity can be combined with PRP’s vast usability to create significant and mindblowing advances in modern medicine.

This includes skincare as well, as the PRP that you get from patients can be used in a plethora of ways. Here are a couple of examples of what can be performed by dermatologists and plastic surgeons the world over.

  1. Skin Augmentation

Adding a topical solution of PRP ccombined with microneedling can help to regenerate dying skin cells, and makes skin feel soft. Although this will probably work for most clients, many might want more. For instance, if you want to plump up the face, injecting PRPinto the dermis can help provide both beauty, as well as a healing process.

Although if you want to create volume, you will need a filler. One way to do this is by using a Platelet-Poor Plasma filler, or PPP, which is often left over from the PRP process. You can also use Hyaluronic Adic. A combination of these with PRP have been known to provide wonderful results, with some clinicians boasting a 100% success rate.

  1. Vitiligo Correction

Many companies will shill out millions of dollars to find out how to turn defective cells healthy again. Many are looking into DNA Technology. However, simply utilizing PRPP may provide the same results. Some studies have shown that adding CO2 laser therapy for correcting vitiligo to a PRP treatment can increase it’s effectiveness by 4 times. This can also be beneficial in other areas, such as correcting wrinkles, and even acne scars. So combining PRP treatments are conventional therapies can boost the effects tremendously.

So if PRP can help boost the effects of lasers, it may be able to also boost the effects of other skin therapies as well. It seems like a great opportunity to continue doing the work that you do, but this time it is more effective due to a simple method. This is something that hundreds of skin care facilities are already providing for their clients.

  1. Hair Rejuvenation

Mesotherapy is a common treatment that utilizes microinjections that deliver a medication throughout the skin’s service. This prodecure has been able to provide great quality results by adding peptides and vitamins to the mix as well. However, one of the best ways that you can incorporate this into your practice is by using PRP therapy.

Mesotherapy can also be used to provide an even amount of PRP all over the body, including face, neck, hands, etc. This helps to rejuvenate the skin and reduce wrinkles, discoloration, and stretch marks. However, this works best when it comes to hair loss treatments. In fact, adding PRP with mesotherapy has exceeding the expectations that the industry has set.

This is why we think PRP therapy is something that every skincare clinic should offer. Since hair loss effects both men and women, it is important to try to work to make your treatments as effective as possible. Your patients will benefit from it and satisfaction will rise, is there any other reason to put it off?

“But I Never Heard Of Them!”

Some of these treatments and combinations are incredibly new, so new, that many might not have heard of them before. However, this is why signing up to use them as soon as possible is vital. This way, you can bee a step ahead of the competition when it comes to providing great services.

The demand for PRP is only growing over time, and the sooner you can get on board, the better off your practice will be. If you are interested in learning more about PRP therapy, or checking out our line of PRP equipment, you can do so by going to the Adimarket website and checking it out for yourself.

PRP provides more effective treatments for less time, less money, and more satisfaction. Tons off practices have been putting their trust in this treatment and have been reaping the benefits long term. PRP is here to stay, so are you ready to seize the potential of this great medical revolution?, 

PRP is a powerful means of regenerating tissues, and has pretty a pretty large growth in popularity among patients, especially those who suffer from alopecia. This is despite the apparently lack of evidence that supposedly surrounds the treatment.

Is It A Lack Of Evidence Or Just A Lack Of Funding?The lack of widespread research may have more to do with funding than anything else. Many of the studies that are currently out there about PRP were unfunded, especially on the subject of Hair Regeneration. However, despite this lack of funding, the demand for PRP treatments for hair loss is growing at an unprecedented rate.

When it comes to PRP kits, there are three kinds to choose from. Ones that use gels, one that create a buffy coat, and one that creates a buffy coat utilizing a double spin. It is pretty unanimous that the last option creates the most reliable and concentrated form of PRP possible, at 5-7 times the baseline amount of platelets.

This concentration level also has the most nutrients which helps for the regeneration of blood vessels and stem cells. One commonly recommended tactic is to combine PRP hair regeneration with micro-needling with a topical layer of PRP. This may be beneficial in some cases.

Micro-needling is a way to create small amounts of trauma, which the body reacts to via a healing response. This response, mixed with PRP, can help to stimulate the growth of new cells.

In some instances, a dermatologist might have three sessions, with the first two being PRP injections, and the middle one being a micro-needling with a PRP topical solution. However, micro-needling is completely optional. Whether you choose to use this method or not, you will still be injecting the patient with PRP at the scalp.  

Combining PRP with an Allograft Matrix

One thing that many hair regeneration experts do is combine PRP with an Allograft matrix. These are often used when healing wounds, as it changes inactive adult stem cells back into an active form. This makes the wounds heal faster.

This is because an allograft acts like a scaffold that proliferates cell regrowth and speeds up the healing process. Many experts in the fields have noted a high degree of success by using this method.

Allografts are generally made from using the bladder tissue of pigs. However, a better type of allograft is made from amniotic tissues and fluid. This type of allograft can be utilized with little or no chance of being rejected by the body, as opposed to those made from pig bladders.

Medications Vs PRP

The main drugs that are commonly used to regrow hair are Minoxidil and Finasteride. These were designed to be able to prevent male pattern hair loss, but did almost nothing when it came to regrowing lost hair. However, these drugs have been well known to only be temporary solutions, and if the patients stopped taking the drugs, the benefits of them would quickly reverse. These are also not 100% effective at stopping hair loss either, but it can slow the progression.

However, PRP is different. It may actually be the only treatment on the market that has been clinically proven to regrow hair and heal hair follicles. This means that it only only slows down hair loss, but actually helps with hair growth.

Many may ask how temporary the solution is, saying that the other drugs on the market are just temporary solutions. However, many pateints report that a PRP and allograft combination treatment was able to give them great results that lasted for nearly half a decade or more with just one treatment. However, each patient is indeed different.

Aside from drugs, we only had one other choice when it came to hair loss, and that was hair transplants. This is why PRP has been growing in popularity in hair regrowth groups lately. Although those other treatments are not obsolete in the slightest, adding PRP therapy can be both beneficial and safe to patients in the long run.

Some people combine the two, and use PRP alongside  Minoxidil and Finasteride with little to no side effects seen to date. You can even combine PRP with laser light scalp stimulation therapy, but that is up to you.

So Try It Out

PRP for hair regeneration, skin rejuvination, and even facelifts is going strong with no sign of stopping. Many dermatologists have already taken the plunge, and since this treatment is not going anywhere anytime soon, it may behoove you to join in on it too.

For more information about PRP including equipment, check out the Adimarket website. We provide great tools for any practice to utilize.

Magellan Autologous

                                                                            Magellan Autologous Platelet Separator

Global Stem Cells Group and its subsidiary Adimarket named representatives for Magellan Autologous Platelet Separator in Latin America and Middle East.

 MIAMI, Nov. 29, 2017— Global Stem Cells Group (GSCG), a world leader in stem cell and regenerative medicine, and its subsidiary Adimarket have been named to represent the Magellan Autologous Platelet Separator in Latin America and Middle East.

Developed by Arteriorcyte Medical Systems, a leading medical device company headquartered in Hopkinton, Mass., the Magellan Autologous Platelet Separator is a high-tech, automated dual spin processing system designed for use in clinical laboratories or intraoperatively at the point-of-care for safe and rapid preparation of high-quality, platelet-rich plasma (PRP) as well as platelet poor plasma (PPP).

Global Stem Cells Group CEO Benito Novas says the Magellan system is a perfect fit for GSCG and Adimarket’s ever-growing list of high-tech regenerative medicine products and equipment, made available to physicians and qualified practitioners through the Adimarket online store.

“We share Arteriocyte’s commitment to research and development of blood component technology to advance treatments that benefit patients in the field of regenerative medicine,” Novas says. “The Magellan system furthers GSCG’s drive to invest in platelet separation technologies that focus on the development of new surgical applications for PRP and elevates these technologies to the next level.”

The fully-automated Magellan system is specifically designed to fractionate blood at bedside without a need for manual manipulation. At the end of its cycle, the Magellan PRP is delivered into a collection syringe, ready for immediate application.

As an industry leader, Adimarket added the Magellan Autologous Platelet Separator System to its online regenerative medicine store to allow physicians to meet the specific needs of each patient with fully customizable product volumes and platelet concentrations. The system can be programmed to deliver a volume of 3 – 10 mL from each processing cycle, allowing practitioners to customize the concentration per mL within the PRP.  The Magellan system is approved for three processing cycles per disposable separation chamber, allowing for a maximum of 30 mL of product.

For more information, visit the Adimarket regenerative medicine online store website, email, or call 305-560-5337.

About Global Stem Cells Group:

Global Stem Cells Group (GSCG) Global Stem Cells Group (GSCG) is a worldwide network that combines seven major medical corporations, each focused on furthering scientific and technological advancements to lead cutting-edge stem cell development, treatments, and training. The united efforts of GSCG’s affiliate companies provide medical practitioners with a one-stop hub for stem cell solutions that adhere to the highest medical standards.

Global stem cell’s mission is to be the largest recognized stem cell and regenerative medicine network in the world.

About Adimarket:

Adimarket, Inc., a division of the Global Stem Cells Group, is a one-stop, cost-competitive online marketplace for quality regenerative medicine equipment and supplies for physicians and health care professionals.

Adimarket was founded to provide practitioners the tools they need to practice regenerative medicine in a medical office setting. Motivated by a firm belief in the impact stem cell medicine can have when dispensed in a doctor’s office, Adimarket provides physicians with the tools they need to provide patients with cutting-edge treatments.

About Arteriorcyte Medical Systems:
Magellan Autologous Platelet Separator
Arteriocyte Medical Systems, Inc. is a leading medical device company committed to developing and marketing novel medical products to help patients heal faster. Established in 2007 by Arteriocyte, Inc. and DW Healthcare Partners, Arteriocyte Medical Systems is devoted to providing innovative solutions to patients and medical professionals to address serious unmet medical needs particularly in cardiac, orthopedic and vascular surgeries.


Magellan Autologous platelet separator